Why is epiduo forte so expensive

Epiduo, which contains benzoyl peroxide 2.5%, is less likely to cause adverse effects compared with products containing benzoyl peroxide 5 to 10%.^2,4 The addition of adapalene has not been shown to increase the risk of adverse effects compared with benzoyl peroxide alone.⁴ Erythema, scaling, dryness, stinging, and burning commonly occur at the beginning of therapy and usually subside within four weeks.^1,2 Sun and wind exposure will increase these symptoms, especially in patients who are sensitive to sunlight.

As with other topical acne medications, less frequent application; use of moisturizers; and avoidance of alcohol-containing products, other acne products, and abrasive cleaners may minimize adverse effects. Avoiding mucous membranes and the corners of the eyes, nose, and mouth when applying the product is thought to decrease the likelihood of irritation.

Adapalene/benzoyl peroxide can cause bleaching if it is transferred to clothing or bedding.¹